January 14, 2016

Age Related Muscle Loss

By Dave Hansen



Nathan LeBrasseur, M.S., Ph.D., Associate Professor of Physiology, Mayo Clinic College of Medicine, PM&R was interviewed recently at the Fourth Annual Symposium on Regenerative Medicine in Rochester, Minnesota.

Dr. LeBrasseur discussed his research at the Mayo Clinic Center on Aging.

He believes there are fundamental underpinnings to diseases like sarcopenia, which is the age related loss of muscle and other conditions like Alzheimer’s disease or osteoporosis.

They are gaining an understanding of a process known as cellular senescence; a process in which cells stop dividing and become very toxic to the tissues they are living in because of the factors they secrete.

This could have implications for muscle and regeneration.

In related work, Dr. LeBrasseur is actively involved in a multicenter clinical trial looking at ways to improve muscle health and enhance physical function in late life and hoping it will also impact metabolism and frailty in older persons.

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