Posts (4)

Wed, May 10 4:41pm · Gene Therapy for Cartilage Regeneration

Hi, Nancy. Thank you for your interest in clinical trials. I’ve enclosed links that may assist you in findings studies as they become posted and would be available to you.

Mayo Clinic Clinical Trials: http://clinicaltrials.mayo.edu/ you may search by location/condition/healthy volunteer etc. (you may need to fill out some information about yourself i.e.: gender/age). Once you find a study that you would be interested in participating in, there will be a phone number and/or email to contact a study coordinator who will then go thru the eligibility and any remuneration with you. I have found the following studies which may be of interest to you http://www.mayo.edu/research/clinical-trials/search-results?keyword=Thumb%20arthritis&status=open-unknown .

Please be aware that Clinical studies differ from medical care. When you visit your doctor, he or she diagnoses and treats your current illness or condition. During clinical studies, researchers are trying to gather new knowledge that will help them improve medical care for people in the future. You may also like to call our Regenerative Medicine Consult Service – for general information and appointments Toll Free: 844-276-2003.

I would also recommend searching the National Institutes of Health-Clinical Trials website at http://clinicaltrials.gov . It is a large database containing information about research throughout the world. You can search for keywords as well as view specific study summaries. Each study will then list criteria for that particular study and contact information.

You may also like to register on line at https://www.researchmatch.org/ this is a site that brings both volunteers and researchers together.

I hope you find this information helpful.

Thu, Apr 13 9:46am · Mayo Clinic expands sports medicine facility in Minneapolis

Mayo Clinic Square building in Minneapolis, Minnesota

(Originally posted on the Mayo Clinic News Network)

Mayo Clinic announced today that it is expanding its services, space and other capabilities at its sports medicine facility in downtown Minneapolis to meet the growing demand for its expertise.

Construction on the 16,000-square-foot project at Mayo Clinic Square is expected to begin in late April.

“This project builds on our commitment to patients in the Twin Cities area by providing more convenient and accessible sports medicine services,” says Edward Laskowski, M.D., co-director of Mayo Clinic Sports Medicine. “This expansion allows us to serve our patients better by tapping Mayo Clinic’s expertise, cutting-edge technology, research and educational capabilities.”

Physician services and select radiology services will be on the second floor, while MRI, rehabilitation and performance services will be on the third floor. The expansion calls for:

  • Additional capacity for services from orthopedic, primary care and physical medicine and rehabilitation sports specialists (Specialized clinics include regenerative medicine, cartilage restoration, hip arthroscopy, multi-ligament knee reconstruction, injury prevention, and performance training for the athlete.)
  • Additional sports medicine physician staff
  • An advanced X-ray system that incorporates cone beam CT (and 3-D capabilities), fluoroscopy and fully robotic digital X-ray
  • A dual-energy X-ray absorptiometry system to measure bone density and body composition
  • A second suite for musculoskeletal ultrasound and regenerative medicine procedures, such as platelet-rich plasma and bone marrow aspirate concentrate injections, and minimally invasive ultrasound technology to treat chronic soft tissue and tendon damage
  • A biomechanics and movement analysis laboratory for sports medicine research
  • Fifteen new patient exam rooms

Mayo Clinic Sports Medicine is adding a physical medicine and rehabilitation sports medicine fellowship in Minneapolis, starting this summer. Over the next two years, four physical therapists trained in sports medicine will join Mayo Clinic Square’s staff.

“Mayo Clinic Sports Medicine’s integrated and multidisciplinary team approach helps athletes of all ages and abilities optimize their performance, minimize risk and treat injury,” says Michael Stuart, M.D., co-director of Mayo Clinic Sports Medicine. “This expansion will ensure that patients continue to get the world-class, whole-person care that is the hallmark of Mayo Clinic.”

“The expansion allows the Department of Radiology to provide additional services,” says Kimberly Amrami, M.D., division chair, Musculoskeletal Radiology, and physician lead for Mayo Clinic Square imaging. “We will be able to offer CT services for sports medicine applications, including those for extremities and the spine. Patients and clients will be able to receive bone density and body composition data. We will be able to deliver full-service sports medicine imaging services on-site.”

During construction, Mayo Clinic Sports Medicine at Mayo Clinic Square will be open regular business hours.

Mayo Clinic is a global leader in sports and musculoskeletal injury prevention and rehabilitation, concussion research, diagnostic and interventional ultrasound, and surgical and nonsurgical management of sports-related injuries. Mayo Clinic collaborates with Exos, a premier training organization based on mindset, nutrition, movement and recovery. Mayo Clinic and Exos staff work together to deliver sports medical care and human performance training solutions.

Mayo Clinic opened its 22,000-square-foot sports medicine facility at Mayo Clinic Square in October 2014. It is the preferred medical provider for the Minnesota Timberwolves and Minnesota Lynx.

“Mayo Clinic is excited to be part of downtown Minneapolis,” says John Wald, M.D., medical director, Mayo Clinic Public Affairs and Marketing. “This expansion reflects our continuing commitment to the health and wellness of the community, and the ongoing redevelopment and revitalization of this area.”

About Mayo Clinic
Mayo Clinic is a nonprofit organization committed to clinical practice, education and research, providing expert, whole-person care to everyone who needs healing. For more information, visit mayoclinic.org/about-mayo-clinic or newsnetwork.mayoclinic.org.

Thu, Apr 13 9:41am · Man moves paralyzed legs using device that stimulates spinal cord

Graphic of spine surgery procedure

(Originally posted on the Mayo Clinic News Network)

Mayo Clinic researchers used electrical stimulation on the spinal cord and intense physical therapy to help a man intentionally move his paralyzed legs, stand and make steplike motions for the first time in three years.

The case, the result of collaboration with UCLA researchers, appears today in Mayo Clinic Proceedings. Researchers say these results offer further evidence that a combination of this technology and rehabilitation may help patients with spinal cord injuries regain control over previously paralyzed movements, such as steplike actions, balance control and standing.

“We’re really excited, because our results went beyond our expectations,” says neurosurgeon Kendall Lee, M.D., Ph.D., principal investigator and director of Mayo Clinic’s Neural Engineering Laboratory. “These are initial findings, but the patient is continuing to make progress.”

The 26-year-old patient injured his spinal cord at the sixth thoracic vertebrae in the middle of his back three years earlier. He was diagnosed with a motor complete spinal cord injury, meaning he could not move or feel anything below the middle of his torso.

The study started with the patient going through 22 weeks of physical therapy. He had three training sessions a week to prepare his muscles for attempting tasks during spinal cord stimulation. He was tested for changes regularly. Some results led researchers to characterize his injury further as discomplete, suggesting dormant connections across his injury may remain.

Following physical therapy, he underwent surgery to implant an electrode in the epidural space near the spinal cord below the injured area. The electrode is connected to a computer-controlled device under the skin in the patient’s abdomen. This device, for which Mayo Clinic received permission from the U.S. Food and Drug Administration for off-label use, sends electrical current to the spinal cord, enabling the patient to create movement.

After a three-week recovery period from surgery, the patient resumed physical therapy with stimulation settings adjusted to enable movements. In the first two weeks, he intentionally was able to:

  • Control his muscles while lying on his side, resulting in leg movements
  • Make steplike motions while lying on his side and standing with partial support
  • Stand independently using his arms on support bars for balance

Intentional, or volitional, movement means the patient’s brain is sending a signal to motor neurons in his spinal cord to move his legs purposefully.

“This has really set the tone for our post-surgical rehabilitation – trying to use that function the patient recovered to drive even more return of abilities,” says Kristin Zhao, Ph.D., co-principal investigator and director of Mayo Clinic’s Assistive and Restorative Technology Laboratory.

The Mayo researchers worked closely with the team of V. Reggie Edgerton, Ph.D., at UCLA on this study, which replicates earlier research done at the University of Louisville. The Mayo study marks the first time a patient intentionally controlled previously paralyzed functions within the first two weeks of stimulation.

The data suggest that people with discomplete spinal cord injuries may be candidates for epidural stimulation therapy. However, more research is needed into how a discomplete injury contributes to recovering function.

Teams from Mayo Clinic’s departments of Neurosurgery and Physical Medicine and Rehabilitation, and the Division of Engineering collaborated on this project.

“While these are early results, it speaks to how Mayo Clinic researchers relentlessly pursue discoveries and innovative solutions that address the unmet needs of patients,” says Gregory Gores, M.D., executive dean of research, Mayo Clinic.  “These teams highlight Mayo Clinic’s unique culture of collaboration, which brings together scientists and physician experts who work side by side to accelerate scientific discoveries into critical advances for patient care.”

Co-authors are:

  • Peter Grahn, Ph.D., Mayo Clinic
  • Igor Lavrov, M.D., Ph.D., Mayo Clinic
  • Dimitry Sayenko, Ph.D., UCLA
  • Meegan Van Straaten, Mayo Clinic
  • Megan Gill, Mayo Clinic
  • Jeffrey Strommen, M.D., Mayo Clinic
  • Jonathan Calvert, Mayo Clinic
  • Dina Drubach, Mayo Clinic
  • Lisa Beck, Mayo Clinic
  • Margaux Linde, Mayo Clinic
  • Andrew Thoreson, Mayo Clinic
  • Cesar Lopez, Mayo Clinic
  • Aldo Mendez, M.D., Mayo Clinic
  • Parag Gad, Ph.D., UCLA
  • Yury Gerasimenko, Ph.D., UCLA

The research was funded by Craig H. Neilsen Foundation, Jack Jablonski BEL13VE in Miracles Foundation, Mayo Clinic Center for Clinical and Translational Sciences, Mayo Clinic Rehabilitation Medicine Research Center, Mayo Clinic Transform the Practice, and The Grainger Foundation.

The Broccoli Foundation and Christopher and Dana Reeve Foundation supported the UCLA team.

Drs. Edgerton, Gerasimenko and Gad have a financial interest in NeuroRecovery Technologies.

About Mayo Clinic Proceedings
Mayo Clinic Proceedings is a monthly peer-reviewed medical journal that publishes original articles and reviews dealing with clinical and laboratory medicine, clinical research, basic science research, and clinical epidemiology. Mayo Clinic Proceedings is sponsored by Mayo Foundation for Medical Education and Research as part of its commitment to physician education. It publishes submissions from authors worldwide. The journal has been published for more than 80 years and has a circulation of 130,000. Articles are at mayoclinicproceedings.org.

About Mayo Clinic
Mayo Clinic is a nonprofit organization committed to clinical practice, education and research, providing expert, whole-person care to everyone who needs healing. For more information, visit mayoclinic.org/about-mayo-clinic or newsnetwork.mayoclinic.org.

Oct 19, 2016 · Andrea Cheville, M.D., of Mayo Clinic elected to the National Academy of Medicine

chevilleAndrea Cheville, M.D., physical medicine and rehabilitation researcher and director of the Cancer Rehabilitation Program at Mayo Clinic, has been elected to the National Academy of Medicine.

Being elected to the academy, formerly known as the Institute of Medicine, is considered one of the highest honors in health and medicine.

Dr. Cheville is one of two Mayo Clinic physicians to be elected this year. Orthopedic surgeon and researcher Michael Yaszemski, M.D., Ph.D., also was selected.

“To have colleagues from distinct practice areas recognized in the same year is an incredible honor for them individually and for Mayo Clinic as a whole,” says John Noseworthy, M.D., president and CEO, Mayo Clinic. “Such recognition underscores the commitment of our physician-scientists in advancing research to address unmet patient needs, educating the next generation of physicians and scientists, and providing unparalleled care for patients and their families.”

Dr. Cheville is well-known for developing patient-centric, cost-effective strategies for delivering   supportive care to people with complex and chronic conditions. Her clinical and research interests are cancer rehabilitation, lymphedema and palliative medicine. She has examined factors that cause people with cancer and other chronic conditions to lose function and shown that these factors are widely undertreated, especially in the outpatient setting.

Read the full news release on the Mayo Clinic News Network.

Contact Us · Privacy Policy